X - 선조사가 태내백서의 구개기형성립과정에 관한 실험적 연구
An Experimental Study on Radiation Induced Palatal Malformation
황광세, 김재덕, 이동주,
소속 상세정보
황광세 ( Hwang Gwang-Se ) - 조선대학교 치과대학 치주과학교실
김재덕 ( Kim Jae-Deok ) - 조선대학교 치과대학 구강악안면방사선학교실
이동주 ( Lee Dong-Joo ) - 조선대학교 치과대학 교정학교실
KMID : 0353319820050010015
Abstract
An experimental study was made on the radiation induced malformation, with special reference to the realation-ship between fetal malformation and radiation and radiation damage to the palate,
The change was examined macroscopically using strain mice.
The study was performed in following ways :
Of the duplex uterus of the mouse, the embryos of one side was used for inducing malformations, and the other side was to be saved as the control . the same environment and the same pregnant stage were considered to be essential for this study.
In order to irradiate the one side of the horns, a 1.6cm thick lead plate having a window covering it, was used to shield the other part of the body.
To find the critical period developing cleft palate embryos of the 10½th, 11½th and 12½th day of gestation were irradiated with 193,242 and 290 rads.
The results were as follows
I. The 11½th day of gestation showed the highest incidence of cleft . palate by x-irradiation was considered as the critical period developing cleft palate.
2. It was remarkable that the weight of. embryos irradiated decreased in accordance with increasing of dosage.
3. Incidence of cleft palate did not show the proportional relationship to the increase of dosage.
4. Feature of cleft palate induced by x-irradiation showed the failure of union between paltal process and alveolar process bilaterally and between bilateral palatal processes.
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